Get Alzheimer's disease and related disorders annual. / 2004 PDF

By Philip Scheltens MD PhD, Serge Gauthier, Philip Scheltens, Jeffrey L. Cummings

content material: Innervation of Senile Plaques: A hyperlink among Amyloid and Neurofibrillary Pathology? B. Delatour, V. Blanchard, L. Pradier, and C. Duyckaerts Vascular elements and Alzheimer's illness, I. Skoog, D. Gustafson, and M. Sjogren The position of White topic Lesions in Dementia, L. Pantoni Subclassification of gentle Cognitive Impairment in examine and medical perform, S. Gauthier and J. Touchon Neuropsychiatric points of gentle Cognitive Impairment, T.J. Hung and J.L. Cummings Cognitive Rehabilitation in light Cognitive Impairment and Prodromal Alzheimer's illness, M. van der Linden, A.-C. Juillerat, and X. Delbeuck medical Trial layout within the Age of Dementia remedies: demanding situations and possibilities, E. Mohr, C.L. Barclay, R. Anderson, and J. consistent Ethics of study in Dementia, J. Karlawish Memantine: A Glutamate Antagonist for remedy of Alzheimer's ailment, R. Smith Doody, B. Winbald, and V. Jelic administration of Comorbidity in Alzheimer's disorder, R. Jones dietary Prevention in Alzheimer's illness, O. Guerin and B. Vellas Index

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Sjögren M, Gustafsson K, Syversen S et al. Treatment with simvastatin in patients with Alzheimer’s disease lowers both alpha—and beta-cleaved APP. Dement Geriatr Cogn Dis 2003; 16:25–30. 128. Peila R, Rodriguez BL, Launer LJ. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: the Honolulu-Asia Aging Study. Diabetes 2002; 51:1256–1262. 129. Leibson C, Rocca W, Hanson V et al. Risk of dementia among persons with diabetes mellitus: a population-based cohort study. Am J Epidemiol 1997; 145: 301–308.

DIAGNOSIS OF ALZHEIMER’S DISEASE IN RELATION TO CEREBROVASCULAR DISEASE 135. 136. 137. 138. 139. 140. 141. 142. 143. 144. 145. 146. 147. 148. 149. 150. 151. 152. 153. 43 Stern DM, Yan SD, Yan SF, Schmidt AM. Receptor for advanced glycation endproducts (RAGE) and the complications of diabetes. Ageing Res Rev 2002; 1: 1–15. Yan S, Chen X, Fu J et al. RAGE and amyloid-β peptide neurotoxicity in Alzheimer’s disease. Nature 1996; 382:685–691. Vitek MP, Bhattacharya K, Glendening JM et al. Advanced glycation end products contribute to amyloidosis in Alzheimer disease.

Ann Neurol 2000; 47:632–640. Bugiani O, Giaccone G, Frangione B et al. Alzheimer patients: preamyloid deposits are more widely distributed than senile plaques throughout the central nervous system. Neurosci Lett 1989; 103:263–268. Holcomb LA, Gordon MN, Jantzen P et al. Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits. Behav Genet 1999; 29:177–185. 20 INNERVATION OF SENILE PLAQUES 88. 89. 90. 91.

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